• Home
  • E-Submission
  • Sitemap
  • Contact Us
Asian-Australas J Anim Sci. Search

CLOSE


Go to Top Go to Bottom
Asian-Australas J Anim Sci > Accepted Articles
DOI: https://doi.org/10.5713/ajas.18.0624    [Accepted] Published online January 4, 2019.
Effect of reduced energy density of close-up diets on metabolites, lipolysis and gluconeogenesis in Holstein cows
Wenming Huang1,2  , Libin Wang1,2, Shengli Li2,*, Zhijun Cao2,*
1College of Animal Science, Southwest University, Chongqing 402460, China
2State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Correspondence:  Shengli Li,Email: lisheng0677@163.com
Zhijun Cao,Email: caozhijun@cau.edu.cn
Received: 21 August 2018   • Revised: 11 November 2018   • Accepted: 20 December 2018
Abstract
Objective: An experiment was conducted to determine the effect of reduced energy density of close-up diets on metabolites, lipolysis and gluconeogenesis in cows during the transition period.

Methods

Thirty-nine Holstein dry cows were blocked and assigned randomly to three groups, fed a high energy density diet [HD, 1.62 Mcal of net energy for lactation (NEL)/kg dry matter (DM) ], a medium energy density diet (MD, 1.47 Mcal NEL/kg DM), or a low energy density diet (LD, 1.30 Mcal NEL/kg DM) prepartum; they were fed the same lactation diet to 28 days in milk (DIM). All the cows were housed in a free-stall barn and fed for ad libitum intake.

Results

The reduced energy density diets decreased the blood insulin concentration and increased nonesterified fatty acids (NEFA) concentration in the prepartum period (p < 0.05). They also increased the concentrations of glucose, insulin and glucagon, and decreased the concentrations of NEFA and β-hydroxybutyrate during the first 2 weeks of lactation (p < 0.05). The plasma urea nitrogen concentration of both prepartum and postpartum was not affected by dietary energy density (p > 0.05). The dietary energy density had no effect on mRNA abundance of insulin receptors, leptin and peroxisome proliferator-activated receptor-γ in adipose tissue, and phosphoenolpyruvate carboxykinase, carnitine palmitoyltransferase-1 and peroxisome proliferator-activated receptor-α in liver during the transition period (p > 0.05). The HD cows had higher mRNA abundance of hormone-sensitive lipase at 3 DIM compared with the MD cows and LD cows (p = 0.001). The mRNA abundance of hepatic pyruvate carboxykinase at 3 DIM tended to be increased by the reduced energy density of the close-up diets (p = 0.08).
Conclusion
The reduced energy density diet prepartum was effective in controlling adipose tissue mobilization and improving the capacity of hepatic gluconeogenesis postpartum.
Keywords: Transition Cow; Dietary Energy Density; Lipolysis; Gluconeogenesis; Blood Metabolites


ABOUT
SPECIALTIES
BROWSE ARTICLES
FOR AUTHORS AND REVIEWERS
Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul
08776, Korea   TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2019 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Developed in M2community

Close layer
prev next