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Asian-Australas J Anim Sci > Volume 31(8); 2018 > Article
Nonruminant Nutrition and Feed Processing
Asian-Australasian Journal of Animal Sciences 2018;31(8): 1267-1274.
DOI:    Published online December 19, 2017.
Effects of zinc sources and levels of zinc amino acid complex on growth performance, hematological and biochemical parameters in weanling pigs
Yi Zhang1, Terry Lynn Ward2, Fei Ji3, Chucai Peng1, Lin Zhu1, Limin Gong1, Bing Dong1,* 
1State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China
2Zinpro Corporation, Eden Prairie, MN 55344, USA
3Zinpro (Wuxi) Additives Bio-Technology Co., LTD., Shanghai 201100, China
Correspondence:  Bing Dong, Tel: +86-131-4619-5659, Fax: +86-10-62733688, Email:
Received: 7 October 2017   • Revised: 4 November 2017   • Accepted: 18 December 2017
Objective: The objective of the study was to investigate the effects of zinc amino acid complex (ZnAA) on growth performance, hematological and biochemical parameters in weanling pigs.


In Exp. 1, a total of 216 Duroc×Landrace×Large White weanling pigs were assigned randomly to 6 dietary treatments. Each treatment had 6 replicates (pens) with 6 pigs each. The diets were corn-soybean meal based with supplementation of 0, 20, 40, 80, 120 mg Zn/kg from ZnAA or 40 mg Zn/kg from feed-grade zinc sulfate. The experiment lasted 42 days. In Exp. 2, a total of 180 weanling pigs were assigned randomly to 3 dietary treatments supplemented with 0, 80, or 800 mg Zn/kg from ZnAA.


In Exp. 1, pigs fed 40 to 80 mg Zn/kg from ZnAA had higher (p<0.05) average daily gain (ADG) than the unsupplemented group during d 0 to 14. During d 0 to 42, the pigs fed 20 to 120 mg Zn/kg from ZnAA had increased (p<0.05) ADG. Pigs fed 20 to 120 mg/kg Zn from ZnAA had lower feed:gain (p<0.05), increased the activity of serum Cu-Zn superoxide dismutase on d 14, and increased serum Zn levels on d 42 (p<0.05). In Exp. 2, pigs fed diets with 800 mg Zn/kg had increased average daily feed intake during d 15 to 28 (p<0.05) compared to the unsupplemented group. During d 0 to 28, the pigs fed supplemental Zn had increased ADG (p<0.05). On d 14 and d 28, pigs fed supplemental Zn had higher the serum alkaline phosphatase activities (p<0.05). No significant differences were observed in the hematological parameters and organ indices.
Supplementation with 20 to 80 mg/kg Zn from ZnAA improved the growth performance in weaned pigs. The piglets can tolerate up to 800 mg/kg Zn from ZnAA with limited potential health effects.
Keywords: Zinc Amino Acid Complex; Weanling Pigs; Performance; Hematological Parameters; Biochemical Parameters

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