Go to Top Go to Bottom
Animal Breeding and Genetics
Asian-Australasian Journal of Animal Sciences 2011;24(9): 1179-1183.
DOI: https://doi.org/10.5713/ajas.2011.10453    Published online August 24, 2011.
Association of Polymorphisms in Fecundity Genes of GDF9, BMP15 and BMP15-1B with Litter Size in Iranian Baluchi Sheep
F. Moradband, G. Rahimi, M. Gholizadeh
Abstract
The incidence of mutation in three loci of GDF9, BMP15 and BMP15-1B and their effects on litter sizes was evaluated in Baluchi sheep. Wild-type alleles were detected for BMP15 and BMP15-1B loci and all individuals were found to be as non-carriers for FecB and FecXG mutations but, a G to A nucleotide substitution was found in GDF9 locus. The frequency of FecG+ (0.82) wild type allele was higher than the frequency of FecG1 (0.18) mutant allele and the frequencies of FecG+/FecG+, FecG+/FecG1 and FecG1/FecG1 genotypes were 0.72, 0.20 and 0.08, respectively in GDF9 locus. The heterozygous (FecG+/FecG1) and homozygous (FecG+/FecG+) non-carrier ewes had 0.35 and 0.21 more lambs than the homozygous (FecG1/FecG1) carrier ewes, respectively (p<0.05). In addition to the finding of segregation of non-additive gene effect on litter size in the previous study in Baluchi sheep, these findings for the first time shows that the FecG1 gene has a major effect on litter size in this breed.
Keywords: BMP15; BMP15-1B; GDF9; Litter Size; Baluchi Sheep


Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul 08776, Korea   
TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2020 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Close layer
prev next