Go to Top Go to Bottom
Animal Reproduction and Physiology
Asian-Australasian Journal of Animal Sciences 2009;22(3): 350-355.
DOI: https://doi.org/10.5713/ajas.2009.80381    Published online March 4, 2009.
Effect of Arachidonic Acid on Production of Laminin and Connexin of Granulosa Cells from Chicken Pre-hierarchical Follicles
Yanmei Jin, Tu Quang Tan, Caiqiao Zhang*
Correspondence:  Caiqiao Zhang,
Arachidonic acid (AA) is a polyunsaturated fatty acid that is a normal constituent of membrane lipids in animal cells. In addition to its role as a precursor of prostaglandins, AA itself may play an important role in the regulation of cell function. The effect of AA on functions of granulosa cells was investigated in pre-hierarchical small yellow follicles of laying hens. Immuno-cytochemical staining showed that AA (10-7-10-5 M) increased the expression of the extracellular matrix glycoprotein laminin, gap junction connexin 43 and protein kinase C (PKC). Therefore, mediated by the PKC signal pathway, AA may regulate the intercellular communication of granulosa cells and follicular development by increasing the expression of laminin and connexin.
Keywords: Granulosa Cell; Arachidonic Acid; Laminin; Connexin 43; Chicken
METRICS Graph View
  • 2 Crossref
  • 2 Scopus
  • 1,897 View
  • 8 Download
Related articles

Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul 08776, Korea   
TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2020 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Close layer
prev next