• Home
  • E-Submission
  • Sitemap
  • Contact Us
Asian-Australas J Anim Sci. Search

CLOSE


Go to Top Go to Bottom
Asian-Australas J Anim Sci > Volume 18(9); 2005 > Article
Animal Breeding and Genetics
Asian-Australasian Journal of Animal Sciences 2005;18(9): 1221-1225.
DOI: https://doi.org/10.5713/ajas.2005.1221    Published online December 1, 2005.
Single Nucleotide Polymorphisms on Peroxisome Proliferator-activated Receptor Genes Associated with Fatness Traits in Chicken
H. Meng, J. G. Zhao, Z. H. Li, H. Li
Abstract
The peroxisome proliferator-activated receptors (PPARs) are members of a superfamily of nuclear hormone receptors. Lots of studies in rodents and humans have shown that PPARs were involved in lipid metabolism and adipocyte differentiation. The main objective of this work was to detect the single nucleotide polymorphisms (SNPs) in whole coding regions of peroxisome proliferator-activated receptor alpha (PPAR-慣) and gamma (PPAR-款) genes with approach of single strand conformation zolymorphism (SSCP) in the chicken population of Arber Acres broiler, Hyline layer and three Chinese native breeds (Shiqiza, Beijing You, Bai`er). Two SNPs of C1029T and C297T were found in chicken PPAR-慣 and PPAR-款 genes respectively and each SNP found three genotypes in the experimental populations. The results showed that the distribution frequency of 3 genotypes in Arber Acres broiler, Hyline layer and Chinese native breeds had significant differences on the PPAR-慣 and PPAR-款 gene respectively (p<0.01). Furthermore, in the PPAR-慣 gene, the results of least square estimation for genotypes and body composition traits showed the BB genotype birds had higher abdominal zat weight (AFW) and percentage of abdominal fat (AFP) than AA genotype birds (p<0.05). From these we conjecture the PPAR-慣 and PPAR-款 genes were suffered intensive selection during the long term commercial breeding and the PPAR-慣 gene may be a major gene or linked to the major genes that impact chicken fat metabolism and the SNPs could be used in molecular assistant selection (MAS) as a genetic marker for the chicken fatness traits.
Keywords: PPARs; SSCP; SNPs; Fatness traits; MAS; Chicken


ABOUT
SPECIALTIES
BROWSE ARTICLES
FOR AUTHORS AND REVIEWERS
Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul
08776, Korea   TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2019 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Developed in M2community

Close layer
prev next