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Animal Breeding and Genetics
Asian-Australasian Journal of Animal Sciences 2004;17(8): 1033-1038.
DOI: https://doi.org/10.5713/ajas.2004.1033    Published online January 1, 2004.
Bootstrap Analysis and Major DNA Markers of BM4311 Microsatellite Locus in Hanwoo Chromosome 6
Jung-Sou Yeo, Jae-Woo Kim, Hyo-Sub Shin, Jea-Young Lee
Abstract
LOD scores related to marbling scores and permutation test have been applied for the purpose detecting quantitative trait loci (QTL) and we selected a considerable major locus BM4311. K-means clustering, for the major DNA marker mining of BM4311 microsatellite loci in Hanwoo chromosome 6, has been tried and five traits are divided by three cluster groups. Then, the three cluster groups are classified according to six DNA markers. Finally, bootstrap test method to calculate confidence intervals, using resampling method, has been adapted in order to find major DNA markers. It could be concluded that the major markers of BM4311 locus in Hanwoo chromosome 6 were DNA marker 100 and 95 bp.
Keywords: Bootstrap Analysis; LOD Score; QTL; Permutation Test; K-means Clustering
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