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Animal Breeding and Genetics
Asian-Australasian Journal of Animal Sciences 2001;14(12): 1665-1669.
DOI: https://doi.org/10.5713/ajas.2001.1665    Published online December 1, 2001.
Mapping a Quantitative Trait Locus for Growth and Backfat on Porcine Chromosome 18
X. L. Wu, C. Lee, J. Jiang, Y. L. Peng, S. L. Yang, B. N. Xiao, X. C. Liu, Q. S. Shi
A QTL was localized near S0120 on porcine chromosome 18. The QTL was significant (p<0.05) for average daily gain (ADG) of body weight and backfat thickness (BFT). The estimates of additive and dominance effects for the QTL were 0.0135 kg/day (p<0.001) and 0.0138 kg/day (p>0.5) for ADG and 1.6115 mm (p<0.001) and 0.9281 mm (p>0.05) for BFT. The location of this QTL coincided with a few growth hormone pathway genes. This study suggested that a QTL allele probably resulted from a mutation responsible for physiological lipase deficiency favoring obesity. This QTL might be important to obesity as well as growth in pigs.
Keywords: Genome Scan; Mixed Models; Backfat; Obesity; Pigs

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