Go to Top Go to Bottom
Asian-Australas J Anim Sci > Volume 13(6); 2000 > Article
Review Paper
Asian-Australasian Journal of Animal Sciences 2000;13(6): 845-855.
DOI: https://doi.org/10.5713/ajas.2000.845    Published online June 1, 2000.
Implantation in Ruminants: Changes in Pre-Implantation, Maternal Recognition of Pregnancy, Control of Attachment and Invasion
K. Nagaoka, H. Yamaguchi, H. Aida, K. Yoshioka, M. Takahashi, R. K. Christenson, K. Imakawa, S. Sakai
Abstract
As high as 50% of pregnancies are known to fail and the majority of such losses occur during the peri-implantation period. For the establishment of pregnancy in mammalian species, therefore, implantation of the conceptus to the maternal endometrium must be completed successfully. Physiological events associated with implantation differ among mammals. In ruminant ungulates, an elongation of the trophohlast in early conceptus development is required before the attachment of the conceptus to the uterine endometrium. Moreover, implantation sites are restricted to each uterine caruncula where tissue remodeling, feto-maternal cell fusion and placentation take place in a coordinated manner. These unique events occur under strict conditions and are regulated by numerous factors from the uterine endometrium and trophoblast in a spatial manner. Interferon-tau (IFN-t), a conceptus-derived anti-luteolytic factor, which rescues corpus luteum from its regression in ruminants, is particularly apt to play an important role as a local regulator in coordination with other factors, such as TGF-棺, Cox-2 and MMPs at the attachment and placentation sites.
Keywords: Ruminants; Attachment; Placentation; PGF2慣; IFN?; TGF棺
TOOLS
METRICS Graph View
  • 1 Crossref
  • 3 Scopus
  • 1,770 View
  • 16 Download
Related articles


Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul 08776, Korea   
TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2019 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Close layer
prev next