• Home
  • E-Submission
  • Sitemap
  • Contact Us
Asian-Australas J Anim Sci. Search


Go to Top Go to Bottom
Asian-Australas J Anim Sci > Volume 9(6); 1996 > Article
Animal Reproduction and Physiology
Asian-Australasian Journal of Animal Sciences 1996;9(6): 695-700.
DOI: https://doi.org/10.5713/ajas.1996.695    Published online December 1, 1996.
Possible roles of submandibular salivary glands on ovarian steroids responsiveness of mouse mammary glands
I. S. Yuh, B. B. Jang
This experiment was to determine the effect of sialoadenectomy on the ability of the mammary gland development to response to ovarian steroids, estrogen and progesterone, stimulus in vivo. Body weights did not differ between sham-operated and sialoadenectomized mice within 0 to 18 day estradiol + progesterone (E + P) injection (p>0.05). Sialoadenectomy reduced mammary development scores from 4.6 to 3.9 or from 4.4 to 3.8 in comparison with those of sham-operated mice for the 12 or 18 day E + P injection(p<.05), however, sialoadenectomized mice with 0, 1, 3 or 6 day of E + P injection slightly decreased mammary development scores relative to those of sham-operated mice. These results indicate that the endocrine factor secreted from submandibular salivary gland appears to be required for the mammary development to respond fully to estradiol and progesterone. Similar results were obtained in the measurement of mammary DNA contents. Mammary DNA contents of sialoadenectomized mice were significantly decreased relative to those of sham-operated mice for the 6, 12 or 18 day E + P injections. Overall results suggest that salivary gland-secreted endocrine factor, presumably epidermal growth factor(EGF), was mammogenic and should interact with ovarian steroids in mammary development.
Keywords: Sialoadenectomy; EGF; Estrogen; Progesterone; Mammary Development
Share :
Facebook Twitter Linked In Google+
METRICS Graph View
  • 0 Crossref
  •  0 Scopus
  • 1,524 View
  • 1 Download

Editorial Office
Asian-Australasian Association of Animal Production Societies(AAAP)
Room 708 Sammo Sporex, 23, Sillim-ro 59-gil, Gwanak-gu, Seoul
08776, Korea   TEL : +82-2-888-6558    FAX : +82-2-888-6559   
E-mail : jongkha@hotmail.com               

Copyright © 2019 by Asian-Australasian Journal of Animal Sciences. All rights reserved.

Developed in M2community

Close layer
prev next