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Swine Nutrition and Feed Technology
Asian-Australasian Journal of Animal Sciences 1992;5(1): 29-32.
DOI: https://doi.org/10.5713/ajas.1992.29    Published online March 1, 1992.
The effects of prostaglandins and indomethacin on ovulation in the perfused fowl ovary
K. Tanaka, T. Higuchi, M. Tawarazumita, F. Hertelendy
The effects of prostaglandins (PG) and indomethacin, a PG synthesis inhibitor, on ovulation in the perfused fowl ovary were studied. Laying hens were killed by cutting the jugular vein 18-19 h before expected ovulation of the second follicle of a clutch sequence. The cannulated ovary was dissected free and connected with a recycling perfusion apparatus. Agents to be studied for their effects on ovulation were added to the perfusion fluid. PGF2慣 at 0.1 and 1 mg/l induced ovulation, with a success rate of 25% and 30%, respectively. The same doses of PGF2 were effective at 60% and 63%, respectively. Indomethacin partially blocked gonadotrophin-induced ovulation. It is suggested that PGs may play a supportive role in the process of follicular rupture in the domestic fowl.
Keywords: Fowl Ovary; Perfusion; Prostaglandin; Indomethacin

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