|
Genome-wide association research on the reproductive traits of Qianhua Mutton Merino sheep |
Jiarong Li1 
, Limin Sun2
, Jiazhi Sun3
, Huaizhi Jiang1,*
|
1Jilin Agricultural University, Changchun, China
2Jilin Academy of Agricultural Sciences, Changchun, China
3Anhua Agricultural Insurance Co., Ltd., Changchun, China |
Correspondence:
Huaizhi Jiang, Tel: +86-17543067888, Email: sheepandgoatjlau@sina.com
|
|
Received: 14 September 2023 • Revised: 26 December 2023 • Accepted: 1 February 2024 |
|
|
| Abstract |
Objective
Qianhua Mutton Merino sheep is a new breed of meat wool sheep cultivated independently in China. In 2018, it was approved by the state and brought into the national list of livestock and poultry genetic resources. Qianhua Mutton Merino sheep has the common characteristics of typical meat livestock varieties with rapid growth and development in the early stage and high meat production performance.The objective of this research is to investigate the Genome-wide association of the reproductive traits of Qianhua Mutton Merino sheep.
Methods
Qianhua Mutton Merino sheep from the breeding core group were selected as the research object, GWAS was conducted on genes associated with the reproductive traits (singleton or twins, birth weight, age [in days] for sexual maturity, weaning weight, and daily gain from birth to weaning) of Qianhua mutton merino.
Results
Our study findings showed that 151 loci of SNPs were detected, among which 3 SNPs related to birth weight and weaning weight occupied a significant portion of the wide genome. The candidate genes preliminarily obtained were SYNE1, SLC12A4, BMP2K, CAMK2D, IMMP2L, DMD, and BCL2.
Conclusion
151 SNP loci were detected for five traits related to reproduction (including singleton or twins, birth weight, age [in days] at sexual maturity, weaning weight, and daily weight gain from birth to weaning). The functions of these candidate genes were mainly enriched in nucleotide metabolism, metal ion binding, oxytocin signaling pathway, and neurotrophin signaling pathway.
|
| Keywords:
Genome Analysis; Reproductive Traits; Sheep Breeds |
|
PDF Links
Full text via DOI
Download Citation
