Genetic gains and inbreeding coefficients in a Holstein MOET breeding population were predicted under different conditions relating to the distribution of the number of transferable embryos collected per flush using Monte Carlo simulation. The numbers of transferable embryos collected per flush were determined using five distributions (distributions 1, 3, 5, 7 and 9) with different aspects and similar means. Distributions 1, 3, 5, 7 and 9 were assumed to have gamma distribution''''s parameters ( and ) of (1 and 4.4), (3 and 1.47), (5 and 0.88), (7 and 0.63) and (9 and 0.49), respectively. Inbreeding rates were statistically significantly different among distributions but genetic gains were not. Relationships between inbreeding rates and variances of family size could be were clearly distinguished. The highest inbreeding coefficients were predicted in distribution 1 with the largest variance of family size, while distributions 5, 7 and 9 with smaller variance of family size had lower inbreeding coefficients |