Alexopoulos C. 2001. Association of Fusarium mycotoxicosis with failure in applying an induction of parturition program with PGF2-alpha and oxytocin in sows. Theriogenology 55:1745–1757.
Blaney BJ, Bloomfield RC, Moore CJ. 1984. Zearalenone intoxication of pigs. Aust Vet J 61:24–27.
Chang K, Kurtz HJ, Mirocha CJ. 1979. Effects of the mycotoxin zearalenone on swine reproduction. Am J Vet Res 40:1260–1267.
Chaytor AC, Hansen JA, van Heugten E, See MT, Kim SW. 2011. Occurrence and decontamination of mycotoxins in swine feed. Asian Australas J Anim Sci 24:723–738.
Etienne M, Jemmali M. 1982. Effects of zearalenone (F2) on estrous activity and reproduction in gilts. J Anim Sci 55:1–10.
Etienne M, Dourmad JY. 1994. Effects of zearalenone or glucosinolates in the diet on reproduction in sows: A review. Livest Prod Sci 40:99–113.
EFSA. 2004. Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to zearalenone as undesirable substance in animal feed. EFSA J 89:1–35.
Gajecka M, Rybarczykb L, Zwierzchowskia W, Jakimiuka E, Zielonkaa L, Obremskia K, Gajecki M. 2011. The effect of experimental, long-term exposure to low-dose zearalenone mycotoxicosis on the histological condition of ovaries in sexually immature gilts. Theriogenology 75:1085–1094.
Jiang SZ, Yang ZB, Yang WR, Yao BQ, Zhao H, Liu FX, Chen CC, Chi F. 2010. Effects of feeding purified zearalenone contaminated diets with or without clay enterosorbent on growth, nutrient availability, and genital organs in post-weaning female pigs. Asian Australas J Anim Sci 23:74–81.
Jiang SZ, Yang ZB, Yang WR, Gao J, Liu FX, Broomhead J, Chi F. 2011. Effects of purified zearalenone on growth performance, organ size, serum metabolites, and oxidative stress in postweaning gilts. J Anim Sci 89:3008–3015.
Jiang SZ, Yang ZB, Yang WR, Wang SJ, Liu FX, Johnston LA, Chi F, Wang Y. 2012. Effect of purified zearalenone with or without modified montmorillonite on nutrient availability, genital organs and serum hormones in post-weaning piglets. Livest Sci 144:110–118.
Kaliamurthy J, Geraldine P, Thomas PA. 1997. Effects of Zearalenone on food consumption, growing rate, organ weight and serum testosterone level in male rats. J Environ Biol 18:115–120.
LeBlanc GA, Bain LJ, Wilson VS. 1997. Pesticides: multiple mechanisms of demasculinization. Mol Cell Endocrinol 126:1–5.
Milano GD, Becu-Villalobos D, Tapia MO. 1995. Effects of long-term zearalenone administration on spermatogenesis and serum luteinizing hormone, follicle-stimulating hormone, and prolactin values in male rats. Am J Vet Res 56:954–958.
Minervini F, Dell Aquila ME, Maritato F, Minoia P, Visconti A. 2001. Toxic effects of the mycotoxin zearalenone and its derivatives on
in vitro maturation of bovine oocytes and 17 Beta-estradiol levels in mural granulosa cell cultures. Toxicol In Vitro 15:489–495.
Mitak M, Gojmerac T, Mandic B, Cvetnic Z. 2001. Changes in serum concentration of 17-beta estradiol in female rats during estrous cycle after treatment with atrazine and zearalenone. Vet Med 46:145–148.
Mueller SO, Simon S, Chae K, Metzler M, Korach KS. 2004. Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor a (ER
α) and ER
β in human cells. Toxicol Sci 80:14–25.
NRC (National Research Council). 1998. Nutrient Requirements of Swine. 10th edNational Academy Press; Washington, DC, USA:
Obremski K, Gajecki M, Zwierzchowski W, Zielonka L, Otrocka-Domagala I, Rotkiewicz T, Mikołajczyk A, Gajecka M, Polak M. 2003. Influence of zearalenone on reproductive system cell proliferation in gilts. Pol J Vet Sci 6:239–245.
Price WD, Lowell RA, McChsney DG. 1993. Naturally occurring toxins in feedstuffs: Center for Veterinary Medicine Perspective. J Anim Sci 71:2556–2562.
Rainey MR, Tubbs RC, Bennett LW, Cox NM. 1990. Prepubertal exposure to dietary zearalenone alters hypothalamo-hypophysial function but does not impair postpubertal reproductive function of gilts. J Anim Sci 68:2015–2022.
Institute SAS. 2003. SAS/STAT User’s Guide: Version 9.1th ed. SAS Institute Inc; Cary, NC, USA:
Silva JRV, van den Hurk R, de Matos MHT, dos Santos RR, Pessoa C, de Moraes MO, de Figueiredo JR. 2004. Influences of FSH and EGF on primordial follicles during
in vitro culture of caprine ovarian cortical tissue. Theriogenology 61:1691–1704.
Tiemann U, Tomeka W, Schneider F, Vanselowb J. 2003. Effects of the mycotoxins α- and β-zearalenol on regulation of progesterone synthesis in cultured granulosa cells from porcine ovaries. Reprod Toxicol 17:673–681.
Ueno Y. 1991. Biochemical mode of action of mycotoxins. Mycotoxins and Animal Foods. Smith JE, Henderson RS, editorsCRS Press; Boston, MA, USA: p. 437–453.
Wasowicz K, Gajecka M, Calkal J, Jakimiuk E, Gajecki M. 2005. Influence of chronic administration of zearalenoneon on the processes of apoptosis in the porcine ovary. Vet. Med-Czech 50:531–536.
Yang HH, Aulerich RJ, Helferich W, Yamini B, Chou KC, Miller ER, Bursian SJ. 1995. Effects of zearalenone and/or tamoxifen on swine and mink reproduction. J Appl Toxicol 15:223–232.
Yang J, Zhang Y, Wang Y, Cui S. 2007. Toxic effects of zearalenone and α-zearalenol on the regulation of steroidogenesis and testosterone production in mouse Leydig cells. Toxicol In Vitro 21:558–565.
Yu Z, Zhang L, Wu D, Liu F. 2005. Anti-apoptotic action of zearalenone in MCF-7 cells. Ecotoxicol Environ Saf 62:441–446.
Zhang H, Nagasshima H, Goto T. 1997. Natural occurrence of mycotoxins in corn, samples from high and low risk areas for human esophageal cancer in China. Mycotoxin 44:29–35.
Zinedine A, Soriano JM, Moltó JC, Manes J. 2007. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin. Food Chem Toxicol 45:1–18.
Zwierzchowski W, Przybylowcz M, Obremski K, Zielonka L, Skorska-Wyszynska E, Gajecka M, Polak M, Jakimiuk E, Jana B, Rybarczyk L, Gajecki M. 2005. Level of zearalenone in blood serum and lesions in ovarian follicles of sexually immature gilts in the course of zearalenone micotoxicosis. Pol J Vet Sci 8:209–218.